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I am excited to bring you the Spring 2019 issue of US Cardiology Review. This is my second issue as the incumbent Editor-in-Chief, and my first as Member of the Staff, Department of Cardiovascular Medicine at the Cleveland Clinic. I have made a concerted effort in reaching out to colleagues who I have trained and worked with at different stages in my career to contribute to this issue. They are all experts in their respective fields, and I am immensely grateful for their effort in contributing to US Cardiology Review. We all share a common goal: to deliver contemporary science to the practicing clinician in a concise, ready-for-action, succinct format.

Structural heart disease takes center stage in this issue. Somsupha Kanjanauthai et al. discuss what the future holds for transcatheter aortic valve replacement. Mehmet Ali Elbey et al. take an in-depth look at the data from the MITRA-FR and COAPT trials and implications for the contemporary management of patients with secondary mitral regurgitation. Shu-I Lin et al. discuss transcatheter edge-to-edge repair of severe tricuspid regurgitation.

In the interventional cardiology section, Rhian Davies and J Dawn Abbott write about recent advances in percutaneous coronary intervention, Mahesh Anantha Narayanan and Santiago Garcia educate us on the utility of high-sensitivity troponin in the evaluation of patients with acute coronary syndrome, and Michael Megaly et al. discuss the role of drug-coated balloons (versus stents) in small-vessel interventions.

We have an exciting cardiometabolic disorders section in this issue of the journal. Marc P Allard-Ratick et al. discuss the role of high-density lipoprotein cholesterol in cardiovascular outcomes, and Miguel Rodriguez-Ramos writes about diabetic cardiomyopathy.

The cardiomyopathy and electrophysiology sections have an article each on cardiac sarcoidosis by Steven R Sigman and advances in AF by Jeffrey L Turner and Nassir Marrouche, respectively.

The Editor’s Pick for this issue is a stellar piece by Deborah L Nadler and Athena Poppas on the early management of essential hypertension.

I am also excited to announce Radcliffe Cardiology’s foray into a podcast series with the Spring 2019 issue. “Parallax with Ankur Kalra”, US Cardiology Review’s podcast, will bring the journal’s content to life in a conversational, digestible format. We aspire to be the go-to podcast for accessing latest cardiovascular medicine content that will help take care of patients in the most contemporary fashion feasible.

I hope you enjoy reading the latest issue of US Cardiology Review.